Learning and Memory

When making memories, certain neurons form larger, denser connections, according to a study published today (April 26) in Science.

Scientists have long attempted to understand where, and how, the brain stores memories. At the beginning of the 20th century, German scientist Richard Semon coined the term “engram” to describe the hypothetical physical representations of memories in the brain.

6.29.2015

Dr. Ranganath and his team are featured in this Sacramento News & Review article on why our memories are so inaccurate.

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Memories may be maintained in the brain through a mechanism familiar to any engineer—negative and positive feedback loops, according to researchers Sukbin Lim and Mark Goldman at the UC Davis Center for Neuroscience.

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Why do we remember some events, places and things, but not others? Our brains prioritize rewarding memories over others, and reinforce them by replaying them when we are at rest, according to new research from the University of California, Davis, Center for Neuroscience, published Feb. 11 in the journal Neuron.

“Rewards help you remember things, because you want future rewards,” said Professor Charan Ranganath, a UC Davis neuroscientist and senior author on the paper. “The brain prioritizes memories that are going to be useful for future decisions.”

In a study published online in JAMA Psychiatry, John Daniel Ragland, Ph.D. and Cameron Carter, M.D. combined previously established tests for cognitive function with fMRI to pinpoint how memory and brain function change in patients with schizophrenia.

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Just look into the light: not quite, but researchers at the UC Davis Center for Neuroscience and Department of Psychology have used light to erase specific memories in mice, and proved a basic theory of how different parts of the brain work together to retrieve episodic memories. The work was published Oct. 9 in the journal Neuron. 

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A new study from the University of California, Davis, suggests that when our curiosity is piqued, changes in the brain ready us to learn not only about the subject at hand, but incidental information, too.

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Short-term memory is essential for everyday life — whether remembering a phone number while dialing, carrying on a conversation, or forming the basis of long-term memories. Neuroscientists think that short-term memory is based on changes in both the properties of brain cells and the connections, called synapses, between them.

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Before I left the house this morning, I let the cat out and started the dishwasher. Or was that yesterday? Very often, our memories must distinguish not just what happened and where, but when an event occurred — and what came before and after. New research from the University of California, Davis, Center for Neuroscience shows that a part of the brain called the hippocampus stores memories by their "temporal context" — what happened before, and what came after.

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Charan Ranganath got into memory research to help people with brain damage due to Alzheimer's disease, trauma or other causes. That work has now earned Ranganath, a professor in the Department of Psychology and Center for Neuroscience at the University of California, Davis, a $40,000 fellowship from the John Simon Guggenheim Memorial Foundation, one of 175 awarded to scientists, artists and scholars by the foundation this year.

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