UC Davis Receives $15 Million Grant to Study the Effects of Maternal Infection on Risk for Psychiatric Illness in Offspring

The National Institute of Mental Health (NIMH) has awarded a $15.7 million grant to the UC Davis Silvio O. Conte Center, one of only 15 Conte Centers nationwide.

Psychiatric illnesses and neurodevelopmental disorders, including schizophrenia, affect 15-20 percent of the population worldwide, yet current treatments are at best only partially effective. The UC Davis Conte Center was first established in 2016 through the Center for Neuroscience to determine how maternal infection increases risk for these disorders and to identify new targets for novel treatments.

Researchers Temporarily Turn off Brain Area to Better Understand Function

Capitalizing on experimental genetic techniques, researchers at the California National Primate Research Center, or CNPRC, at the University of California, Davis, have demonstrated that temporarily turning off an area of the brain changes patterns of activity across much of the remaining brain.

The research suggests that alterations in the functional connectivity of the brain in humans may be used to determine the sites of pathology in complex disorders such as schizophrenia and autism.