Robert Berman, Ph.D.

Robert Berman

Position Title
Professor Emeritus

  • Neurological Surgery

Neurodevelopmental Disorders and Brain Injury

Research Summary

Robert F. Berman, Ph.D. is Professor and Vice Chair for Research in the Department of Neurological Surgery, a member of the Center for Neuroscience and on the faculty of the M.I.N.D. Institute.  He is Director of Research for the Neurotrauma Research Laboratories at UC Davis and Co-Director of the Rodent Behavioral Testing Core in the UC Davis  Intellectual and Developmental Disabilities Research Center (IDDRC).  Dr. Berman is a member of the Executive Committee of the  Neuroscience Graduate Program, serves as Neuroscience Program Master Advisor, and is also a member of the Pharmacology/Toxicology Graduate Program. 

Dr. Berman’s laboratory studies neurodevelopmental and neurodegenerative disease, with a focus on cellular mechanisms of brain injury associated with these disorders.   A major research program is focused on the study of Fragile X-associated Tremor/Ataxia (FXTAS).  FXTAS is a late developing neurodegenerative disease due to an expanded CGG trinucleotide repeat in the 5’-untranslated region of the FMR1 gene.  This leads to the development of tremors, ataxia, neuropsychological problems including depression, and dementia in some patients.  Ubiquitin staining intranuclear inclusions in neurons and astrocytes are pathophysiological hallmarks of FXTAS, and are shown in the Figure below.  Dr. Berman’s laboratory is using transgenic CGG KI mice to model FXTAS and to understand the molecular mechanisms that underlie the neuropathology and neurobehavioral deficits in FXTAS.  Both inducible and conditional mouse models are under development and study to determine which cells type (e.g., neurons versus glia) are critical to development of disease, as well as the potential for reversing the symptoms and progression of FXTAS by appropriate pharmacological or gene-targeted therapies. 

A second area of research examines the effects of neonatal toxin exposure (e.g., polybrominated diethyl ethers, PCB’s, ethanol) on brain development and behavior using animal models.  His laboratory has recently developed a set of behavioral testing procedures to evaluate social behaviors and social interactions in rodents in order to provide useful models of for the study of neurodevelopment disorder, including autism. 

Finally, Dr. Berman’s laboratory is continuing research on the role of disruption of calcium homeostasis, and N-type voltage gated calcium channels in particular, in the pathophysiology and cell loss that occurs following traumatic brain injury. 

Dr. Berman’s research and training activities have been funded by the NIH for the past 20 years, and he is currently funded by the NIEHS and NINDS.  His research is multidisciplinary, using in vivo and in vitro models of brain injury, and behavioral, histological, electrophysiological and neurochemical methodologies.

Select Publications

2014  Careaga, M., Rose, D., Tassone, F., Berman, R.F., Hagerman, R., & Ashwood, P.  Immune dysregulation as a cause of autoinflammation in fragile x-premutation carriers:  link between FMR1 CGG repeat number and decreased cytokine responses.  PLoS One. 9(4);e94475.  PMID:24718368

2014  Onore, C.E., Schwartzer, J.J., Careaga, M., Berman, R.F. & Ashwood P.  Maternal immune activation leads to activated inflammatory macrophages in offspring.  Brain Behavior Immunity.  28:220-226.  PMID: 24566386.

2014  Pretto, D.I., Kumar, M., Cao, Z., Cunnngham, C.L., durbin-Johnson, B., Qi, L., Berman, r.F., Noctor, S.C., Hagerman, R. & Pessah, I.N.  Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile x mental retardation gen 1 (FMR1) premutation carriers with fragile X-associated tremor ataxia.  Neurobiology of Aging 35:1189-1197.   PMID:24332449

2014 von Leden, R.E., Curley, L.C., Greenberg, G.D., Hunsaker, M.R., Willemsen, R. & Berman, R.F.  Reduced activity-dependent protein levels in a mouse model of the fragile x premutation.  Neurobiology of Learning and Memory. 109:10-168.  PMID:24462720\

2014 Ludwig, A., Espinal, G., Pretto, D., Jamal, A., Arque, G., Tassone, F., Berman, R.F., Hagerman, P.  CNS expression of murine fragile x protein (FMRP) as a function of CGG repeat size.  Human Molecular Genetics.  23(12): 3228-3238.  PMID: 24463622

2014 Berman, R.F., Buijsen, R.A., Usdin, K., Pintado, E., Kooy, r.F., Pretto, D., Pessah, I.N., Nelson, D., Zalewski, Z., Charlet-Bergeurand, N., Willemsen, R., & Huskma, R.K.  Mouse models of the fragile x premutation and FXTAS.  J. Neurodevelopmental Disorders.  **IN PRESS*

2013  Dursun, U.l, Jakubowska, Dogru, E., Van der List, D., Eliboi-Can, B., Chapman, B., Qi, L., & Berman, R.F.  Effects of early postnatal alcohol exposure on the developing retinogenicular projections.  Alcohol, 47: 173-179.  PMID: 23402901

2013  Schwartzer, J.J., Careaga, M., Onore, C.E., Rushakoff, J.A., Berman, R.F. & Ashwood, P.  Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice.  Translational Psychiatry. 36: 17-35. PMID: 23481627

2013 Shahlaie, K., Gurkoff, G.G., Lyeth, B.G., Muizelaar, J.P. & Berman, R.F.  Neuroprotective effects of delayed SNX-185 treatment on secondary hypoxia/ischemia in mechanically-injured cortical neurons.  Restorative Neurology and Neuroscience.  31(2):141-153.  PMID:23247061

2013  Babineau, B.A., Yang, M., Berman, R.F., Crawley, J. N.  Low home cage social behaviors in BTBR T+tj/J mice during juvenile development.  Physiology and Behavior. 114-115:49-54  PMID 23510981

2013  Onore, C., Careaga, M., Babineau, B., Schwartzer, J., Berman, R.F., & Ashwood, P.  Inflammatory macrophage phenotype in BTBR T+tj/J mice.  Frontiers in Neuroscience, &:158:1-9.  PMID:24062633.

2013  Lee, D.J., Gurkoff, G.G., Izadi, A., Berman, R.F., Ekstrom, A.D., Muizelaar, J.P., Lyeth, B.G. & Shahlaie, K.  Medial septal nucleus theta frequency deep brain stimulation improves spatial working memory following traumatic brain injury.  J. Neurotrauma. I30(2): 131-139.  PMID:23016534

2013  Dursun, I., Jakubowska-Dogru, E., Elibol-Can, B., van der List, D., Chapman, B., Qi, L. & Berman, R.F.  Effects of early postnatal alcohol exposure on the developing reginogeniculate projections in C57BL/6 mice.  Alcohol, 47:173-179 PMID:23402901

2013  Gurkoff, G.G., Gahan, J.D., Ghiasvand, R.T., Hunsaker, M.R., Van, K. Feng, J-F., Shahlaie, K. Berman, R.F., Lyeth, B.G. & Folkerts, M.M.  Evaluation of metric, topological and temporal ordering memory tasks after lateral fluid percussion injury in rats.  J. Neurotrauma. 30(4):292-300. doi: 10.1089/neu.2012.2463 PMID: 23140483

2013  Gurkoff, G.G., Shahlaie, K., Lyegh, B.G., & Berman, R.F.  Voltage-Gated Calcium Channel Antagonists and Traumatic Brain Injury, Pharmaceuticals 2013, 6(7): 788-812; doi:10.3390/ph6070788, PMID:24276315

2012  Schluter, E.W., Greco, C.M., Willemsen, R. & Berman, R.F.  Distribution and frequency of intranuclear inclusions in female CGG KI mice modeling the fragile X premutation.  Brain Research, 1472:124-37.  PMID:22796595

2012 Koenig, C.M., Lango, J., Pessah, I.N. & Berman, R.F.  Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice.  Neurotoxicology and Teratology. 34:571-580. PMID:23022914

2012  Brunschweig, D., Golub, M.S., Koenig, C.M., Qi, L, Pessah, I.N., Van de Water, J. & Berman, R.F. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. Journal of Neuroimmunology.  252(1-2):56-65.  PMID:22951357

2012  Schwartzer, J., Koenig, C.M. & Berman, R.F.  Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environmental interactions.  Neurotoxicology and Teratology.  13:17-35..  PMID:23010509

2012  Kaplan, E.S., Cao, Z., Hulsier, S., Tassone, F. Berman, R.F. Hagerman, P.J. & Pessah, I.N.  Early mitochondrial abnormalities in hippocampal neurons cultured from FMR1 premutation mouse model of FXTAS.  J. Neurochemistry.  123(4):613-621.  PMID:22924671

2012  Koenig, C.M., Walker, C., Qi, L., Pessah, I.N. & Berman, R.F.  Lack of Evidence for Neonatal Misoprostol Neurodevelopmental Toxicity in C57BL6/J Mice.  PloS One, 7(6):e3891  PMID:22719983

2012  Hunsaker, M.R., Kim, K., Willemsen, R. & Berman, R.F.  CGG trinucleotide repeat length modulates neural plasticity and spatiotemporal processing in a mouse model of the fragile X premutation.  Hippocampus (Epub ahead of print; DOI 10.1002/hipo.22043). PMID: 22707411

2012  Berman, R.F. , Murray, K.D., Arque, G., Hunsaker, M.R. & Wenzel, H.J.  Abnormal dendrite and spine morphology in primary visual cortex in the CGG KI mouse model of the fragile X premutation.  Epilepsia, 53(Suppl. 1):150-160.  PMID:22612820

2012 Borthwell, R.M., Hunsaker, RM.R., Willemsen, R. & Berman, R.F.  Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation.  Behavioural Brain Research, 233:29-34.  PMID:22561129

2012  Hunsaker, M.R., Hukema, R.K., Arque, G., Berman, R.F., Willemsen, R.  Mouse models of the fragile X premutation and the fragile X associated tremor/ataxia syndrome.  Result Prob. Cell Differentiation.  54:255-269.  PMID:22009357

2012  Woods, R., Vallero, R., Golub, M., Suarez, J., Ta, T-A., Hausi, D., Chi, Lai, Kostyniak, Pl, Pessah, I.N.,  Berman, R.F. & LaSalle, J.  Long-lived epigenetic interactions between periunatal PBDE exposure and Mecp2308 mutation.  Human Molecular Genetics.  21(11):2399-2411. PMID:22343140

2012 Diep, A.A., Hunsaker, M.R., Kwock, R., Kim, K., Willemsen, R. & Berman, R.F.  Female CGG Knock-in mice modeling the Fragile X premutation are impaired on a skilled forelimb reaching task.  Neurobiology of Learning and Memory, 97(2): 229-234.  PMID:22202169

2012 Tassone, F., Greco, C., Hunsaker, M., Berman, R.F., Seritan, A., Gane, L., Macquemont, S., Basuta, K., Jin, L-W, Hagerman, P.J., & Hagerman, R.  Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS.  Genes Brain and Behavior, 11:577-585.  PMID:22463693

2011  Hunsaker, M.R., Greco, C.M., Spath, M.A., Smits, A.P., Navarro, C.S., Tassone, F., Kros, J.M., Severijnen, L.A., Berry-Kravis, D.M., Berman, R.F., Hagerman, P.J., Willemsen, R., Haggerman, R.J. & Hukema, R.K.  Widespread non-central nervous system organ pathology in Fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice.  Acta Neuropathologica, 122(4): 462-479.

2011  Beller, J.A., Gurkoff, G.G., Berman, R.F. & Lyeth, B.G.  Pharmacological enhancement of glutamate transport reduced excitoxicity in vitro.  Restorative Neurology and Neuroscience. 2011, 29: 331-346. 

2011  Hunsaker, M.R., Greco, C.M., Tassone, F., Berman, R.F., Willemsen, R., Hagerman & R.J., Hagerman, P.J. Rare intranuclear inclusions in the brains of three older adult males with fragile X syndrome: Implications for the spectrum of frragile X-associated disorders. Journal of Neuropathology and Experimental Neurology. 70(6), 462-469.

2011  Ta, T.A., Koenig, C.M., Golub, M.S., Pessah, I.N., Qi, L., Aronovk, P.A. & Berman, R.F.   Bioaccumulation and behavioral effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice.   Neurotoxicology and Teratology, 33, 393-404.

2011  Dursun, I., Jakubowska-Dogru, E., van der List, D., Liets, L.C. Coombs, J.L. & Berman, R.F.   Effects of early postnatal exposure to ethanol on retinal ganglion cell morphology and numbers of neurons in the dorsolateral genulate of mice.   Alcohol: Clinical and Experimental Research, 35(11), 2062-2074.

2011  Berman, R.F., Koenig, C.M., Hunsaker, M.R., Pessah, N.P. & LaSalle, J.M.   Neurodevelopmental toxicology and autism spectrum disorders. Chapter 21. In: C. Wang and Slikker, W. Jr), Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies and Mechanisms. John Wiley and Sons, Inc., 439-476.  

2011  Hunsaker, R.H., Von Leden, R.E., Ta, T.B., Goodrich-Hunsaker, N.J., Arque, G., Kyoungmi, K., Willemsen, R., Berman, R.F.   Motor Deficits on a Ladder Rung Task in Male and Female Adolescent and Adult CGG Knock-in Mice.   Behavioral Brain Research, 222(1):117-121.

2011  Greco, C.M., Navarro, D.S., Hunsaker, M.R., Maezawa, I., Shuler, J.F., Tassone, F., Delany, M., Au, J.W., Berman, R.F., Jin, L-W., Schumann, Hagerman, P.J. & Hagerman, R.J.  Neuropathological features in the hippocampus and cerebellum of three older men with fragile X syndrome  Molecular Autism, 2(2),1-13.

2011  Cunningham, C.L., Cedeno, M., Porras, N.E., Prakash, A.N., Angelastro, J.M., Willemsen, R., Hagerman, P.J., Pessah, I.N., Berman, R.F. & Noctor, S.C.  Premutation CGG-repeat expansion of the Fmr1 gene impair mouse neocortical development.  Human Molecular Genetics, 20(1), 64-79.

2010  Chen, Y., Tassone, F., Berman, R.F., Hagerman, P.J., Willemsen, R. & Pessah, I.N.  Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration.  Human Molecular Genetics, 19(1), 196-208.

2010 Bauman, M.D., Crawley, J.N. & Berman, R.F.  Autism: Animal Models.  In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd. Chichester. pp1-10, DOI: 10.1002/9780470015902.a0022368.

2010 Fedor, M., Berman, R.F., Muizelaar, J.P. & Lyeth, B.G.  Hippocampal theta dysfunction after lateral fluid percussion injury.  J. Neurotrauma, 27, 1605-1615.  PMID: 20597686

2010 Hunsaker, M.R., Goodrich-Hunsaker, N.J., Willemsen, R. & Berman, R.F.  Temporal order deficits in female CGG KI mice heterozygous for the fragile x premutation.  Behavioural Brain Research.  213(2):263-268.

2010 Wenzel, H.J., Hunsaker, R., Greco, C., Willemsen, R. & Berman, R.F.  Intranuclear inclusions in neurons and astrocytes in the mouse model of the Fragile X premutation.  Brain Research, 1318, 155-166.

2010 Shahlaie, K., Lyeth, B.G., Gurkoff, G.G., Muizelaar, J.P & Berman, R.F.  Neuroprotective effects of selective N-type VGCC blockade on stretch injury induced calcium dynamics in cortical neurons.  J. Neurotrauma, 27(1), 175-187.  (Cover image for this issue)

2009 Hunsaker, R., Willemsen, R. & Berman, R.F.  Progressive spatial processing deficits in a mouse model of the Fragile X Premutation.  Behavioral Neuroscience.  123(6), 1315-1325.

2009 Berman, R.F.  Seizure termination and the postseizure refractory period.  Encyclopedia of Basic Epilepsy Research.  Vol. 3, 1320-1327.

2009 Berman, R.F. & Willemsen, R.  Mouse models of Fragile X-associated Tremor/Ataxia.  J. Investigative Medicine.  57(8), 837-841, 2009.

2009 Kim, K.H., Inan, S.Y., Berman, R.F. & Pessah, I.N.  Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation.  toxicology and Applied Pharmacology, 237(2): 168-177, 2009.

2008 Berman, R.F., Pessah, I.N., Mouton, P.R., Mav, D. & Harry, J.  Low-level thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice.  Toxicological Sciences.  101(2):294-2008.

2008 Zhao, X., Gorin, F.A., Berman, R.F. & Lyeth, B.G.  Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats.  J. Neurotrauma.  25(10): 1196-1205.

2008 Parks, E.A., McMechan, A.P., Hannigan, J.P. & Berman, R.F.  Environmental enrichment alters neurotrophin levels after fetal alcohol exposure in rats.  Alcoholism:  Clinical and Experimental Research.  32(10):1741-1751.

2008  Brouwer, J.R., Huizer, K., Severijnen, L.A., Hukema, R.K., Berman, R.F., Oostra, B.A. & Willemsen, R.  CGG-repeat length and neuropathological and molecular correlates in a mouse model for fragile X-associated tremor/ataxia syndrome.  J. Neurochemistry.  107:1671-1682.

2008 Pessah, I.N., Seegal, R.F., Lein, P.J., LaSalle, J. Yee, B.K., Van de Water, J. & Berman, R.F.  Immunologic and neurodevelopmental susceptibilities of autism.  NeuroToxicology.  29(3): 532-545.

2007 Folkerts, M.M., Parks, E., Dedman, J., Kaetzel, M., Lyeth, B.G. & Berman, R.F. Phosphorylation of calcium calmodulin-dependent protein kinase II following traumatic brain injury in rats. J. Neurotrauma, 24(4): 638-650, 2007

2007 Jaubert, P.J., Golub, M.S., Lo, Y.Y., Germann, S.L., Dehoff, M.H., Worley, P.F., Kang, S.H., Scharz, M.K., Seeburg, P.H. and Berman, R.F. Complex, multimodal behavioral profile of the Homer1 knockout mouse. Genes, Brain and Behavior. 6: 141-154, 2007.

2007 Hannigan, HJ, O'Leary-Moore, Sk, & Berman, R. F. Postnatal environmental or experiential amelioration of neurobehavioral effects of perinatal alcohol exposure in rats. Neuroscience and Biobehavioral Reviews, 31:202-211, 2007.

2006 Burke, K.A., Cheng, Y., Baogang,k L., Petrov, A., Pushkar, J. Berman, R.F., Reuhl, R.K. & DiCicco-Bloom, E. Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E. Neurotoxicology, 27(6): 970-81, 2006.

2006 Greco, C.M., Berman, R.F., Martin, R.M., Tassone, F., Schwartz, P.H., Chang, A., Trapp, B.D., Iwahashi, C., Brunberg, J. Grigsby, J., Hessl, D., Becker, E.J., P{apazian, J., Leehey, M.A., Hagerman, R.J. & Hagerman, P.J. Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain, 129, 243-255, 2006.

2006 Zhong, C., Zhao, X., Van, K.C., Bzdega, T., Smyth, A., Zhou, J., Kozikowski, A.P., Jiang, J., O-Connor, W.T., Berman, R.F., Neale, J.H. & Lyeth, B.G. NAAG peptidase inhibitor increases dialysate NAAG and Reduces Glutamate, Aspartate and GABA levels in the dorsal hippocampus following lateral fluid percussion injury in the rat. J. Neurochemistry, 97(4), 1015-25, 2006.

2006 Lapanantsain, S., Chongthammakun, S., Floyd, C.L., Berman, R.F. Effects of 17B-estradiol on intracellular calcium changes and neuronal survival after mechanical strain injury in neuronal-glial cultures. Synapse, 60(5), 406-10, 2006.

2006 O'Leary-Moore, S.K., McMechan, A.P., Mathison, S.N., Berman, R.F., & Hannigan, J.H. Reversal learning after prenatal or easly postnatal alcohol exposure in juvenile and adults rats. Alcohol, 38(2), 99-110.

2005 Van Putten, H.P., Bouwhuis, M.G., Muizelaar, J.P., Lyeth, B.G. & Berman, R. F. Diffusion weighted imaging of Edema following traumatic brain injury in rats: Effects of hypoxia. J. Neurotrauma, 22(8), 857-872, 2005

2005 Dietrich, K.N., Eskenazi, B., Schantz, S., Yolton, K. Rauh, V.A., Johnson, C.B., Alkon, A., Canfield, R. L., Pessah, I.N. & Berman, R.F. Principles and practices of neurodevelopmental assessment in children: Lessions learned from the centers for children's environmental health and disease prevention research. J. Environmental Health Perspectives, 113(10), 1437-46, 2005

2005 McGaraughty, S.P., Berman, R. F., Cowart, M. & Jarvis, M. F. Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. In press, Current Topics in Medicine Chemistry, 5(1), 43-58, 2005.

2005 Aden, U., O'Connor, W. T. & Berman, R. F. Changes in adenosine metabolites and adenosine receptors in the kindled rat brain. Neuroreport, 15(10), 1585-1589, 2005.

2005 Viant, M.R., Lyeth, B.G., Miller, M.G. & Berman, R.F. An NMR metabolomic investigation of early metabolic disturbances following traumatic brain injury in a mammalian model. NMR Biomed. 2005 Dec;18(8):507-16.

2005 German, T.S., Berman, R.F., Lee, I. & Kesner, R.P. Patterns of hippocampal cell loss based on subregional lesions of the hippocampus. Brain Res. 1065(1-2):1-7, 2005.

2003 Rismanchi, N., Floyd, C. L., Berman, R.F. and Lyeth, B.G. Cell death and long-term maintenance of neuron-like state after differentiation of rat bone marrow stromal cells: A comparison of protocols. Brain Research, 991(1-2), 46-55, 2003

2003 Zhao, X., Ahram, A., Berman, R.F., Muizelaar, J. P. & Lyeth, B. G. Early loss of astrocytes after experimental traumatic brain injury. Glia, 44:140-152, 2003.

2004 Hallam, T. M., Floyd, C. L., Folkerts, M. M., Lee, L. L., Gong, Q-Z, Lyeth, B. G., Muizelaar, J. P. and Berman, R. F. Comparison of behavioral effects and acute neuronal degeneration in rat lateral fluid percussion and weight drop brain injury models. J. Neurotrauma, 21(4), 521-539, 2004.

2004 Lee, L.L., Gallo, E., Lyeth, B.G., Muizelaar, J.P. & Berman, R. F. Neuroprotection in the rat lateral fluid percussion in model by SNX185, an N-type voltage gated calcium channel blocker. Experimental Neurology, 90:70-78, 2004

2001 Lyeth, B. G., Gong, Q-Z, Shields, S., Muizelaar, J. P. and Berman, R. F. Group I metabotropic glutamate antagonist reduces acute neuronal degeneration and behavioral deficits after traumatic brain injury in rats. Experimental Neurology, 169, 191-1, 2001

2001 Zwienenberg, M., Gong, Q-Z, Berman, R. F., Muizelaar, J. P. and Lyeth, B. G. The effects of Group II and III metabotropic glutamate receptor activation on neuronal injury in a rodent model of traumatic brain injury. Neurosurgery, 48(5) 1119-1127, 2001.

2001 Hannigan, J.H., Berman, R.F. Alcohol embryofetopathy in rats and the principles of teratology: Illuminating hippocampal dysfunction. In: R. Vogel, J. Fanghanel, Th. Koppe (Eds). Aspects of Teratology, Vol 2, Tectum-Verlag, Marburg, German

2001 Berman, R. F., Aden, U., and O'Connor, W. T. Increased adenosine release and metabolism during seizures in rats. Proceedings of the 9th International Conference on In Vivo Methods: Monitoring Molecules in Neuroscience., pp392-394, 2001.

2000 Berman, R. F. & Hannigan, J. H. Hippocampal damage following prenatal alcohol exposure in rats. Hippocampus. 10:94-110, 2000.

2000 Berman, R. F., Fredholm, B. B., Aden, U. & O'Connor, W. R. Evidence for increased adenosine release and metabolism in the hippocampus of rats during seizures. In Press, Brain Research, 872(1-2): 44-53, 2000

2000 Hannigan, J. H. & Berman, R. F. Amelioration of alcohol-related neurodevelopmental disorders in rats: Exploring and environmental treatments. Neurotoxicology and Teratology, 22, 103-111, 2000.

2000 Berman, R. F., B. H. Verveij and J. Paul Muizelaar. Neurobehavioral protection by the calcium channel blocker SNX111 in a rat model of diffuse brain injury. J. Neurosurg. 93: 831-838, 2000


Department of Neurological Surgery, Vice Chair for Research and Director of the Neurotrauma Laboratory

Center for Neuroscience (Steering Committee Member)

Graduate Program in Neuroscience (Master Advisor)

Intellectual & Developmental Disabilities Research Center (Co-Director Rodent Behavioral Assessment Core)

UC Davis M.I.N.D. Institute (Core Faculty)

Center for Children's Environmental Health Neuroscience