TSNE Plot of single-cell RNA sequencing data, representing immune cells from a murine retina at various stages of neurodegeneration

Genes and Molecules

Genes and Molecules

The nervous system is an amazingly complex aggregation of billions of cells and trillions of connections. Each connection, or synapse, is comprised of over a thousand different types of proteins and there is a remarkable diversity of cell and synapse types in the nervous system. Understanding such complexity requires identification of the molecular components, their genetic encoding, and control of their expression in the brain. Dynamic regulation of expression and localization is also a focus of research at this level. The Center for Neuroscience has numerous faculty working at this level. These faculty utilize many models systems, including Drosophila, rodent, non-human primate and human models to make rapid advances in this field.
 

Faculty studying genes and molecules