Kia Shahlaie, M.D., Ph.D.

 Kia  Shahlaie, M.D., Ph.D.


  • Associate Professor
  • Neurological Surgery


Neuromodulation to Promote Cognitive Recovery in Trauma, Epilipsy, and Neurodegenerative Disorders

Select Publications

Pre-clinical and Translational

Septohippocampal Neuromodulation Improves Cognition after Traumatic Brain Injury.Lee DJ, Gurkoff GG, Izadi A, Seidl SE, Echeverri A, Melnik M, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth BG, Shahlaie K.J Neurotrauma. 2015 Nov 15;32(22):1822-32.

A comparative study of human and rat hippocampal low-frequency oscillations during spatial navigation.Watrous AJ, Lee DJ, Izadi A, Gurkoff GG, Shahlaie K, Ekstrom AD.Hippocampus. 2013 Aug;23(8):656-61.

Voltage-gated calcium channel antagonists and traumatic brain injury.Gurkoff G, Shahlaie K, Lyeth B, Berman R. Pharmaceuticals (Basel). 2013 Jun 26;6(7):788-812.

NAAG peptidase inhibitor improves motor function and reduces cognitive dysfunction in a model of TBI with secondary hypoxia.Gurkoff GG, Feng JF, Van KC, Izadi A, Ghiasvand R, Shahlaie K, Song M, Lowe DA, Zhou J, Lyeth BG.Brain Res. 2013 Jun 17;1515:98-107.

Evaluation of metric, topological and temporal ordering memory tasks after lateral fluid percussion injury.  Gurkoff GG, Gahan JD, Ghiasvand R, Hunsaker MR, Van KC, Feng JF, Shahlaie K, Berman RF, Lyeth BG, Folkerts MM.  J Neurotrauma. 2012 Nov 9. [Epub ahead of print]

Medial septal nucleus theta frequency deep brain stimulation improves spatial working memory following traumatic brain injury.  Lee DJ, Gurkoff GG, Izadi A, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth BG, Shahlaie K.  J Neurotrauma. 2012 Sep 27. [Epub ahead of print]

In vitro mechanical strain trauma alters neuronal calcium responses: Implications for posttraumatic epilepsy.  Gurkoff GG, Shahlaie K, Lyeth BG.  Epilepsia. 2012 Jun;53 Suppl 1:53-60.

Post-traumatic hypoxia exacerbates neuronal cell death in the hippocampus.  Feng JF, Zhao X, Gurkoff GG, Van KC, Shahlaie K, Lyeth BG.  J Neurotrauma. 2012 Apr 10;29(6):1167-79.

Neuroprotective effects of selective N-type VGCC blockade on stretch-injury-induced calcium dynamics in cortical neurons.  Shahlaie K, Lyeth BG, Gurkoff GG, Muizelaar JP, Berman RF.  J Neurotrauma. 2010 Jan;27(1):175-87.

Age-related changes in potentiation of evoked responses in CA1 pyramidal cells from the hamster hippocampus.  Shahlaie K, Kargozaran H, Horowitz JM.  Neurosci Lett. 2001 Jan 12;297(2):85-8.



Intraoperative computed tomography for intracranial electrode implantation surgery in medically refractory epilepsy. Lee DJ, Zwienenberg-Lee M, Seyal M, Shahlaie K.J Neurosurg. 2015 Mar;122(3):526-31.

Long-term neurological outcomes in adults with traumatic intracranial hemorrhage admitted to ICU versus floor.Nishijima DK, Melnikow J, Tancredi DJ, Shahlaie K, Utter GH, Galante JM, Rudisill N, Holmes JF.West J Emerg Med. 2015 Mar;16(2):284-90. 

Computed tomography characteristics in pediatric versus adult traumatic brain injury.Sarkar K, Keachie K, Nguyen U, Muizelaar JP, Zwienenberg-Lee M, Shahlaie K.J Neurosurg Pediatr. 2014 Mar;13(3):307-14.

 Decompressive craniectomy using gelatin film and future bone flap replacement. Oladunjoye AO, Schrot RJ, Zwienenberg-Lee M, Muizelaar JP, Shahlaie K.J Neurosurg. 2013 Apr;118(4):776-82.

Intraoperative computed tomography for deep brain stimulation surgery: technique and accuracy assessment.Shahlaie K, Larson PS, Starr PA.Neurosurgery. 2011 Mar;68(1 Suppl Operative):114-24; discussion 124.

A clinical decision rule to predict adult patients with traumatic intracranial haemorrhage who do not require intensive care unit admission.  Nishijima DK, Shahlaie K, Echeverri A, Holmes JF.Injury. 2012 Nov;43(11):1827-32.

Risk factors for posttraumatic vasospasm.  Shahlaie K, Keachie K, Hutchins IM, Rudisill N, Madden LK, Smith KA, Ko KA, Latchaw RE, Muizelaar JP.  J Neurosurg. 2011 Sep;115(3):602-11.

Anemia in the setting of traumatic brain injury: the arguments for and against liberal transfusion.
Utter GH, Shahlaie K, Zwienenberg-Lee M, Muizelaar JP.  J Neurotrauma. 2011 Jan;28(1):155-65.

Hypertonic saline in neurocritical care: Is continuous infusion appropriate?
Muizelaar JP, Shahlaie K.  Crit Care Med. 2009 Apr;37(4):1521-3.

Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: treatment with intraarterial verapamil and balloon angioplasty. Shahlaie K, Boggan JE, Latchaw RE, Ji C, Muizelaar JP. Neurocrit Care. 2009;10(1):61-9.


Associate Professor, Department of Neurological Surgery

Associate Professor, Department of Neurology (joint appointment)

Chair/Director, Bronte Epilepsy Research Program

Director, Functional Neurosurgery

Co-Director, Neurocritical Care

Co-Director, Center for Skull Base Surgery