Dan Ragland, Ph.D.

 Dan  Ragland, Ph.D.

Position

  • Professor
  • Psychiatry and Behavioral Medicine

Learning and Memory in Schizophrenia

Research Summary

Dr. Ragland's work investigates the effect of schizophrenia on brain function during episodic memory encoding and retrieval.  Of particular interest is the role that organizational abilities play in new learning and subsequent memory retrieval, how schizophrenia disrupts these organizational processes, and how these deficits might be remediated to improve patients' frototemporal brain activity and daily function.  His research has used a combination of neuropsychological, functional imaging, and eye tracking techniques to identify the cognitive functions and brain regions underlying these memory processes. Other research and clinical interests include early identification and treatment at individuals at-risk for psychosis.

Select Publications

Wolf, D.H., Gur, R.C., Valdez, J.N., Loughead, J., Elliott, M.A., Gur, R.E., Ragland, J.D. Alterations of fronto-temporal connectivity during word encoding in schizophrenia. Psychiatry Research: Neuroimaging, 154:221-232, 2007.

Ragland, J.D., Yoon, J., Minzenberg, M.J., Carter, C.S.: Neuroimaging of cognitive disability in schizophrenia: Search for a pathophysiological model. International Review of Psychiatry, 19:417-427, 2007.

Ragland, J.D., Moelter, S.T., Bhati, M.T., Valdez, J.N., Kohler, C.G., Siegel, S.J., Gur, R.C., Gur R.E.: Effect of Retrieval Effort and Switching Demand on fMRI Activation During Semantic Word Generation in Schizophrenia. Schizophrenia Research, 99:312-323, 2008.

Ranganath, C., Minzenberg, M., Ragland, J.D.: The Cognitive Neuroscience of Memory Function and Dysfunction in Schizophrenia. Biological Psychiatry, 19:417-427, 2008.

Dickinson D., Ragland, J.D., Gold, J.M., Gur, R.C.: General and Specific Cognitive Deficits in Schizophrenia: Goliath Defeats David? Biological Psychiatry, 64:18-25, 2008.

Gur, R.C., Ragland, J.D., Reivich, M., Greenberg, J., Alavi, A., Gur, R.E.: Regional Differences in the Coupling Between Resting Cerebral Blood Flow and Metabolism May Indicate Action Preparedness as a Default State. Cerebral Cortex, 19:375-382, 2009.

Ragland, J.D., Cools, R., Frank, M., Pizzagalli, D.A., Preston, A., Ranganath, C., Wagner, A.D.: CNTRICS Final Task Selection: Long-term Memory. Schizophrenia Bulletin, 35:197-212, 2009.

Ragland, J.D., Laird A.R., Ranganath, C., Blumenfeld, R.S., Gonzales, S.M., Glahn, D.C.: Prefrontal Activation Deficits During Episodic Memory in Schizophrenia. American Journal of Psychiatry, 166:863-874, 2009.

Leitman, D.I, Wolf, D.H., Ragland, J.D., Laukka, P., Loughead, J., Valdez, J.N., Javitt, D.C., Turetsky, B.I., Gur, R.C. "It's Not What You Say, But How You Say it": A Reciprocal Temporo-frontal Network for Affective Prosody. Frontiers of Human Neuroscience. 4:19, 2010.

Hannula, D.E., Ranganath, C., Ramsay, I.S., Solomon M., Yoon, J., Niendam, T.A., Carter, C.S., Ragland, J.D. Use of Eye Movement Monitoring to Examine Item and Relational Memory in Schizophrenia. Biological Psychiatry, 2010 Jul 29. [Epub ahead of print].

Recent Publications: https://scholar.google.com/citations?user=-F--exQAAAAJ&hl=en